Silicone gel filled breast implants and connective tissue disease: An overview
Connective Tissue Diseases
Prostheses and Implants
The physical and biological properties of silicone gel filled implants and their behavior in vivo is compatible with the hypothesis that they may contribute to the development of connective tissue disease. The association seems most likely with scleroderma; however, there is as yet inadequate epidemiological data to definitively establish causality.