Relation of panic attacks and midsystolic murmurs to over-diagnosis of mitral valve prolapse Academic Article uri icon


MeSH Major

  • Cardiovascular Diseases
  • Diabetes Mellitus, Type 2
  • Hypertrophy, Left Ventricular


  • The symptoms, auscultatory findings, and echocardiographic data associated with a diagnosis of mitral valve prolapse (MVP) made by physicians in the community were examined in 113 consecutive patients. Neither echocardiographic nor auscultatory evidence of MVP was present in 46 (41%) of these patients. Compared with the 67 patients with objective evidence of MVP, the patients with false-positive diagnoses of MVP were younger, more likely to suffer from panic disorder (46% vs 22%, respectively, P < .01), more commonly had an initial diagnosis of MVP based on symptoms (26% vs 7%, respectively, P < .01) and more frequently had nonspecific midsystolic flow murmurs (43% vs 3%, respectively, P < .001). These data suggest that MVP is commonly over-diagnosed in symptomatic young patients, particularly in the presence of panic disorder or midsystolic murmurs on auscultation.

publication date

  • January 1994



  • Academic Article

Additional Document Info

start page

  • 11

end page

  • 15


  • 15


  • 4