Changes in cerebrospinal fluid neurochemistry during treatment of obsessive-compulsive disorder with clomipramine Academic Article uri icon

Overview

MeSH Major

  • Clomipramine
  • Corticotropin-Releasing Hormone
  • Obsessive-Compulsive Disorder
  • Somatostatin
  • Vasopressins

abstract

  • These neuropeptide results coupled with evidence that central administration of corticotropin-releasing hormone, vasopressin, and somatostatin to laboratory animals increases arousal and acquisition of conditioned behaviors whereas central administration of oxytocin has opposite behavioral effects are consistent with a role for these neuropeptides in the pathophysiologic processes and pharmacologic treatment of obsessive-compulsive disorder.

publication date

  • October 1994

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7524463

Additional Document Info

start page

  • 794

end page

  • 803

volume

  • 51

number

  • 10