Pharmacologic-guided trial of sequential methotrexate and thioguanine in children with advanced malignancies Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Neoplasms

abstract

  • Encouraging antitumor effects were produced with this regimen in heavily pretreated patients with lymphoma, particularly Hodgkin's disease (HD). The durations of responses were 17, 13+, 12, 9, and 7+ months. A phase II trial of the MTX/6-TG combination is warranted for the treatment of relapsed lymphoma.

publication date

  • September 1994

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7521908

Additional Document Info

start page

  • 1955

end page

  • 62

volume

  • 12

number

  • 9