Neuropsychologic effects of cranial irradiation, intrathecal methotrexate, and systemic methotrexate in childhood cancer Academic Article uri icon

Overview

MeSH Major

  • Cognition Disorders
  • Cranial Irradiation
  • Methotrexate

abstract

  • CRT, especially when administered with IT-MTX, at currently used dosages was associated with significant neuropsychologic impairment in children. These impairments are most likely to be reflected in nonverbal intelligence, perceptual abilities, and susceptibility to distraction. IT-MTX and SYS-MTX did not result in a consistent pattern of cognitive deficit.

publication date

  • December 1994

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7989937

Additional Document Info

start page

  • 2621

end page

  • 9

volume

  • 12

number

  • 12