Phase II trial of paclitaxel shows antitumor activity in patients with previously treated germ cell tumors Academic Article uri icon

Overview

MeSH Major

  • Germinoma
  • Paclitaxel
  • Salvage Therapy

abstract

  • Paclitaxel has antitumor activity in GCT and warrants continued study in combination chemotherapy. Phase I/II trials will address its role in combination with cisplatin and ifosfamide and as a part of dose-intensive therapy. Furthermore, the study showed that a trial design in which eligibility criteria limits prior therapy was feasible, resulted in the identification of antitumor activity in a new agent, and may be considered in future trials for other promising new agents in GCT.

publication date

  • November 1994

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7525885

Additional Document Info

start page

  • 2277

end page

  • 83

volume

  • 12

number

  • 11