Phase I/II study of iodine 131-labeled monoclonal antibody A33 in patients with advanced colon cancer Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Heterophile
  • Antibodies, Monoclonal
  • Colonic Neoplasms
  • Iodine Radioisotopes
  • Radioimmunotherapy

abstract

  • The A33 antigen appears to be a promising target for radioimmunotherapy of colon cancer. The modest antitumor activity of 131I-mAb A33 in heavily pretreated patients is encouraging because of its lack of toxicity in the bowel, the only antigen-positive normal tissue.

publication date

  • August 1994

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8040668

Additional Document Info

start page

  • 1561

end page

  • 71

volume

  • 12

number

  • 8