Multiple hamartoma syndrome with osteosarcoma Academic Article uri icon

Overview

MeSH Major

  • Bone Neoplasms
  • Hamartoma Syndrome, Multiple
  • Osteosarcoma
  • Thyroid Neoplasms

abstract

  • Multiple hamartoma syndrome, also known as Cowden's disease, is a rare genodermatosis with characteristic mucocutaneous lesions associated with multiple internal abnormalities. We describe a patient having classic dermatologic manifestations of Cowden's disease and multiple neoplasia including follicular adenocarcinoma of the thyroid gland with lung metastasis, intraductal breast carcinoma within a fibroadenoma, and an osteosarcoma. To our knowledge, this is the first reported case of an osteosarcoma in Cowden's disease.

publication date

  • December 1993

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8250698

Additional Document Info

start page

  • 1252

end page

  • 4

volume

  • 117

number

  • 12