In vitro changes in the properties of rabbit colonie muscularis mucosae in colitis Academic Article uri icon

Overview

MeSH Major

  • Colitis
  • Colon
  • Muscle, Smooth

abstract

  • The muscularis mucosae undergoes two significant alterations in colitis: (a) a selective desensitization to the effects of arachidonic acid metabolites and (b) an impairment of its excitation-contraction coupling mechanism. A loss of the ability of the muscularis mucosae to cause mucosal movement and alter luminal surface area may be an important early stage in the pathophysiology of inflammatory bowel disease.

publication date

  • January 1993

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8425678

Additional Document Info

start page

  • 369

end page

  • 76

volume

  • 104

number

  • 2