Early effects of tissue-type plasminogen activator added to conventional therapy on the culprit coronary lesion in patients presenting with ischemic cardiac pain at rest: Results of the thrombolysis in myocardial ischemia (TIMI IIIA) trial Academic Article uri icon

Overview

MeSH Major

  • Chest Pain
  • Coronary Angiography
  • Coronary Disease
  • Tissue Plasminogen Activator

abstract

  • Arteriographically apparent intraluminal thrombus and improvement of the culprit lesion with either of these regimens were only moderately frequent in patients with unstable angina or non-Q wave MI. Substantial improvement of culprit lesions was more frequent with t-PA than with placebo overall and in two prospectively defined subgroups. The clinical relevance of these observations is being tested in the larger, ongoing clinical TIMI IIIB study.

publication date

  • January 1993

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/01.CIR.87.1.38

PubMed ID

  • 8419023

Additional Document Info

start page

  • 38

end page

  • 52

volume

  • 87

number

  • 1