Fluconazole prophylaxis of fungal infections in patients with acute leukemia: Results of a randomized placebo-controlled, double-blind, multicenter trial Academic Article uri icon

Overview

MeSH Major

  • Fluconazole
  • Leukemia
  • Mycoses
  • Neutropenia
  • Opportunistic Infections

abstract

  • Prophylactic fluconazole prevents colonization and superficial infections by Candida species other than Candida krusei in patients undergoing chemotherapy for acute leukemia and is well tolerated. Fluconazole could not be clearly shown to be effective for preventing invasive fungal infections, reducing the use of amphotericin B, or decreasing the number of deaths.

publication date

  • April 1993

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8442620

Additional Document Info

start page

  • 495

end page

  • 503

volume

  • 118

number

  • 7