Ploidy studies by image analysis on fine needle aspirates of the breast Academic Article uri icon

Overview

MeSH Major

  • Breast Neoplasms
  • Ploidies

abstract

  • Quantitative DNA analysis was performed on preoperative fine needle aspirates of 12 breast cancers and 1 benign lesion using the Cell Analysis Systems (CAS) Model 200 image analysis system. The smears were prepared on CAS slides, routinely processed for Papanicolaou staining, and then destained and restained with Feulgen stain after cytologic evaluation. Four cases were DNA diploid, 3 were tetraploid, 1 was diploid/tetraploid, and 5 were aneuploid. When compared to analysis of samples from the resected tumor, both DNA index and S-phase fraction were constant.

publication date

  • January 1993

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8249514

Additional Document Info

start page

  • 923

end page

  • 8

volume

  • 37

number

  • 6