Intestinal transplantation in children under FK 506 immunosuppression Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Endocrine System Diseases
  • Neoplasms

abstract

  • Intestinal transplantation, solitary (n = 3) or in combination with the liver (n = 7), was performed in 10 pediatric patients with intestinal failure. The liver was only replaced if there was liver failure and portal hypertension. Immunosuppression was based on FK 506. Two patients died, one of graft-versus-host disease and one of lymphoproliferative disease. One patient as still in the intensive care unit 1 month posttransplantation due to perioperative complications. The function of the intestinal grafts in the remaining patients is normal. All nutrition and medications including immunosuppression are being administered enterally. This series indicates that small bowel transplantation, alone or in combination with the liver, is feasible in pediatric patients.

publication date

  • January 1993

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/0022-3468(93)90514-L

Additional Document Info

start page

  • 1040

end page

  • 3

volume

  • 28

number

  • 8