The rational pharmacology of digoxin Academic Article Article uri icon

Overview

MeSH Major

  • Cysteine
  • Isoquinolines
  • Neuromuscular Blockade
  • Neuromuscular Nondepolarizing Agents

abstract

  • Although digoxin remains one of the most widely prescribed drugs in the United States, potential pharmacodynamic and pharmacokinetic interactions between this compound and other drugs, diseases, and events commonly encountered in the perioperative period remain largely unappreciated. Furthermore, the therapeutic benefit of discontinuing or initiating digoxin treatment preoperatively remains unclear. We present a basic review of current knowledge regarding digoxin pharmacology and examine those concepts from the perspective of clinical anesthesiologists.

publication date

  • January 1992

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/0952-8180(92)90170-6

PubMed ID

  • 1389200

Additional Document Info

start page

  • 419

end page

  • 35

volume

  • 4

number

  • 5