Biochemical modulation of bolus fluorouracil by PALA in patients with advanced colorectal cancer Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Antineoplastic Combined Chemotherapy Protocols
  • Colorectal Neoplasms

abstract

  • The observed response rate, median survival, and toxicity in this study are similar to those obtained with PALA plus infusional FU and with other methods of FU modulation. Larger phase III studies are needed to compare bolus FU/PALA regimens with other PALA and non-PALA-containing combinations. Our future focus will be attenuate this regimen's toxicity while maintaining or improving its response rates and survival.

publication date

  • December 1992

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 1569447

Additional Document Info

start page

  • 747

end page

  • 52

volume

  • 10

number

  • 5