A phase II trial of biochemical modulation using N‐ phosphonacetyl‐L‐aspartate, high‐dose methotrexate, high‐dose 5‐fluorouracil, and leucovorin in patients with adenocarcinoma of unknown primary site Academic Article Article uri icon

Overview

MeSH Major

  • Mycosis Fungoides
  • Sezary Syndrome

abstract

  • Expected PRPP and UTP metabolite pool shifts were seen when biochemical modulation was performed with these drugs according to this schedule. Because toxicity was mild, more intense dose schedules of 5-FU are planned for future studies.

publication date

  • January 1992

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19921001)70:7<1988::AID-CNCR2820700730>3.0.CO;2-K

PubMed ID

  • 1381991

Additional Document Info

start page

  • 1988

end page

  • 92

volume

  • 70

number

  • 7