Serum antibodies to L-type calcium channels in patients with amyotrophic lateral sclerosis Academic Article uri icon

Overview

MeSH Major

  • Amyotrophic Lateral Sclerosis
  • Autoantibodies
  • Calcium Channels

abstract

  • Antibodies to L-type voltage-gated calcium channels are present in the serum of patients with amyotrophic lateral sclerosis, and antibody titers correlate with the rate of disease progression. Together with previous data, these results suggest a role for autoimmune mechanisms in the pathogenesis of sporadic amyotrophic lateral sclerosis.

publication date

  • December 10, 1992

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 1331790

Additional Document Info

start page

  • 1721

end page

  • 8

volume

  • 327

number

  • 24