Intracellular signalling by 14-hydroxy-4,14-retro-retinol Academic Article uri icon

Overview

MeSH Major

  • Retinoids
  • Vitamin A

abstract

  • In mammals, retinol is the precursor for retinoids, which affect various aspects of morphogenesis and development. However, B lymphocytes, although retinol-dependent, do not use retinoic acid as mediator. Retinol is metabolized by B lymphocytes and other cell lines to optically active 14-hydroxy-4,14-retro-retinol; it is this compound that mediates the growth control. Thus another second messenger molecule, in addition to retinoic acid and retinal, is derived from retinol.

publication date

  • December 1991

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 1749937

Additional Document Info

start page

  • 1654

end page

  • 6

volume

  • 254

number

  • 5038