Hematologic manifestations of systemic mast cell disease: A prospective study of laboratory and morphologic features and their relation to prognosis Academic Article Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Algorithms
  • Biomarkers, Tumor
  • Carcinoma, Squamous Cell
  • Immunohistochemistry
  • Lung Neoplasms

abstract

  • Our prospective study has defined a number of important variables in patients with clinical evidence of mast cell proliferation that can predict both the presence of SMCD and the likelihood of fatal disease. Since recent evidence suggests that mast cells derive from a bone marrow hematopoietic progenitor, SMCD may represent a myeloproliferative condition with the propensity to evolve into a neoplastic granulocytic disorder in a significant minority of patients.

publication date

  • January 1991

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/0002-9343(91)90214-I

PubMed ID

  • 1750431

Additional Document Info

start page

  • 612

end page

  • 24

volume

  • 91

number

  • 6