Indium-111-labeled leukocyte scintigraphy in hemodialysis access-site infection Academic Article uri icon

Overview

MeSH Major

  • Bacterial Infections
  • Hydroxyquinolines
  • Indium Radioisotopes
  • Leukocytes
  • Organometallic Compounds
  • Oxyquinoline
  • Renal Dialysis

abstract

  • Bacterial sepsis, a significant complication of chronic hemodialysis, is generally the result of infection at the vascular access site. We retrospectively reviewed the utility of indium-111-(111In) labeled autologous leukocyte scintigraphy in 26 patients (30 scans) with synthetic vascular grafts, on chronic hemodialysis, in whom hemodialysis access site infection was a diagnostic consideration. Leukocyte scintigraphy correctly identified all fifteen access-site infections; there was one false-positive study, for an overall sensitivity and specificity of 100% and 93%, respectively. Of particular significance is the fact that in nine (60%) of the fifteen access-site infections, physical examination was normal. Our data indicate that 111In-labeled leukocyte scintigraphy is a useful procedure for the diagnosis of hemodialysis access-site infection, and it is especially valuable when physical examination of the access site is normal.

publication date

  • January 1990

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 2106577

Additional Document Info

start page

  • 319

end page

  • 24

volume

  • 31

number

  • 3