Oral squamous cell carcinoma arising in a patient with long-standing lichen planus. A case report Academic Article Article uri icon


MeSH Major

  • Adenocarcinoma
  • Algorithms
  • Biomarkers, Tumor
  • Carcinoma, Squamous Cell
  • Immunohistochemistry
  • Lung Neoplasms


  • The risk of malignant transformation of oral lichen planus remains a controversial point. Many previous reports have been discounted on the basis of inadequate information or lack of histologic confirmation of lichen planus. We report a well-documented case of long-standing cutaneous and oral lichen planus in which squamous cell carcinoma of the dorsal portion of the tongue occurred. There is an apparent difference in the sites of oral carcinomas in patients with lichen planus compared with the general population. This suggests that lichen planus increases the risk of oral cancer in affected sites.

publication date

  • January 1990



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1016/0030-4220(90)90141-E

PubMed ID

  • 2216354

Additional Document Info

start page

  • 282

end page

  • 5


  • 70


  • 3