Expression of the mammalian Na+-independent L System amino acid transporter in Xenopus laevis oocytes Academic Article uri icon

Overview

MeSH Major

  • Phospholipid Transfer Proteins

abstract

  • System L is primarily responsible for the Na+-independent transport of neutral amino acids, those with bulky chains such as leucine, isoleucine, phenylalanine, etc., into mammalian cells. mRNA from rat kidney and human lymphoid cells, when microinjected into Xenopus laevis oocytes, induced expression of this transport system. The expressed transport exhibits characteristics similar to those reported for the System L amino acid transporter from a variety of mammalian cells. Injection of size-fractionated mRNA indicates that the System L transporter in both the rat kidney and human lymphoid cells is encoded by mRNA of about 3 to 4 kb.

publication date

  • January 1989

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/0003-9861(89)90405-0

Additional Document Info

start page

  • 591

end page

  • 6

volume

  • 275

number

  • 2