Doppler echocardiography: application to the assessment of successful thrombolysis of prosthetic valve thrombosis. Academic Article uri icon


MeSH Major

  • Echocardiography, Doppler
  • Heart Diseases
  • Heart Valve Prosthesis
  • Mitral Valve Stenosis
  • Thrombosis


  • Prosthetic valve thrombosis remains a significant problem despite anticoagulation therapy and advances in valve design. Thrombolytic therapy offers an alternative approach to valve replacement in patients with high surgical risk. In this article we discuss three cases in which Doppler echocardiography was used to confirm the diagnosis of prosthetic mitral valve obstruction and serially monitor the response of valvular hemodynamic measurements to thrombolysis with intravenous streptokinase. These cases illustrate how the Doppler technique, in addition to allowing the noninvasive diagnosis of prosthetic valve obstruction, is presently the ideal tool to follow serially the effect of thrombolytic therapy on prosthetic valve function.

publication date

  • March 1989



  • Academic Article



  • eng

PubMed ID

  • 2629867

Additional Document Info

start page

  • 98

end page

  • 101


  • 2


  • 2