Primary signet ring cell adenocarcinoma of the bladder Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma, Mucinous
  • Urinary Bladder
  • Urinary Bladder Neoplasms

abstract

  • Primary signet ring cell adenocarcinoma of the bladder accounts for less than 1 per cent of all primary bladder neoplasms. This tumor is insidious because of its subepithelial infiltrative nature, which makes diagnosis possible only late in the course of the disease. Survival is poor; greater than 50 per cent of the patients are dead within a year after diagnosis. Exenterative procedures offer the only hope of palliation; irradiation and chemotherapy have not been effective. We add 5 cases of primary signet ring cell adenocarcinoma of the bladder and 1 case of high grade transitional cell carcinoma of the bladder with signet ring cell foci to the 14 cases reported in the literature. Pathological correlation supports the origin of this neoplasm from totipotential transitional epithelium.

publication date

  • January 1989

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 2535761

Additional Document Info

start page

  • 17

end page

  • 21

volume

  • 141

number

  • 1