Anti-neutrophil-elastase defenses of the lower respiratory tract in α1-antitrypsin deficiency directly augmented with an aerosol of α1-antitrypsin Academic Article uri icon

Overview

MeSH Major

  • Lung
  • Neutrophils
  • Pancreatic Elastase
  • alpha 1-Antitrypsin
  • alpha 1-Antitrypsin Deficiency

abstract

  • Short-term aerosol administration of human plasma alpha 1-antitrypsin to patients with alpha 1-antitrypsin deficiency is safe and feasible, resulting in a return to normal of anti-neutrophil-elastase defenses in the lower respiratory tract. The aerosol approach, therefore, merits serious long-term evaluation as an alternative to other parenteral forms of administering therapeutic proteins.

publication date

  • January 1989

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 2787611

Additional Document Info

start page

  • 206

end page

  • 12

volume

  • 111

number

  • 3