Inability of computed tomography appearance of recurrent malignant astrocytoma to predict survival following reoperation Academic Article uri icon


MeSH Major

  • Astrocytoma
  • Brain Neoplasms
  • Glioblastoma
  • Neoplasm Recurrence, Local
  • Tomography, X-Ray Computed


  • Computed tomographic (CT) scans of 39 patients who underwent reoperation for recurrent malignant astrocytoma at Memorial Sloan-Kettering Cancer Center from 1980 through 1987 were reviewed and correlated with the patients' clinical course. Histologic diagnosis (anaplastic astrocytoma v glioblastoma multiforme) had a statistically significant impact on survival following reoperation (P = .038). Patients with high preoperative performance status (P = .29), total resection by postoperative CT scan (P = .15), and frontal lobe tumors (P = .17) tended to survive longer following reoperation. The size of the tumor at the time of recurrence did not correlate with survival following reoperation. Patients with a small amount of peritumoral edema at the time of recurrence tended to survive longer, but the effect was small (P = .16). Prognosis following reoperation cannot be accurately predicted on the basis of tumor appearance on CT scan.

publication date

  • January 1989



  • Academic Article



  • eng

PubMed ID

  • 2550591

Additional Document Info

start page

  • 1492

end page

  • 6


  • 7


  • 10