Antenatal treatment of fetal alloimmune cytopenias Academic Article Article uri icon


MeSH Major

  • Astrocytoma
  • Cerebral Ventricle Neoplasms
  • Endoscopy
  • Ependyma
  • Supratentorial Neoplasms
  • Tectum Mesencephali
  • Third Ventricle
  • Ventriculostomy


  • The antenatal use of intravenous immunoglobulin (IVG) was explored in 9 cases of alloimmune cytopenias affecting fetuses. In 7 cases of alloimmune thrombocytopenia, IVG at a dose of 1 gm/kg/week appeared to be uniformly effective in elevating the fetal platelet count and preventing a recurrence of antenatal intracranial hemorrhage (2 cases). In 2 cases of Rh disease the results were more equivocal. There did not appear to be any significant toxicity associated with its use. The mechanism of IVG effect in the successfully treated cases remains uncertain.

publication date

  • July 1989



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1007/BF00320266

PubMed ID

  • 2752171

Additional Document Info

start page

  • 136

end page

  • 8


  • 59


  • 1