Primary sclerosing cholangitis associated with liver atrophy Academic Article Article uri icon

Overview

MeSH Major

  • Klatskin Tumor
  • Nomograms

abstract

  • Of 27 patients with primary sclerosing cholangitis, 4 were found on investigation and subsequently at operation to have gross lobar atrophy. The disease was particularly severe in the hilar region. Three of the four patients were asymptomatic prior to the onset of jaundice. The presence of atrophy precipitated laparotomy to exclude cancer in two cases. Marked disparity in size between liver lobes precluded a hilar approach to relieve extrahepatic obstruction in two patients. Prolonged follow-up excluded coincident malignant disease. Selective liver atrophy should be considered part of the disease spectrum in primary sclerosing cholangitis.

publication date

  • January 1989

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/0002-9610(89)90314-0

PubMed ID

  • 2662789

Additional Document Info

start page

  • 43

end page

  • 7

volume

  • 158

number

  • 1