Primary sclerosing cholangitis associated with liver atrophy Academic Article Article uri icon


MeSH Major

  • Klatskin Tumor
  • Nomograms


  • Of 27 patients with primary sclerosing cholangitis, 4 were found on investigation and subsequently at operation to have gross lobar atrophy. The disease was particularly severe in the hilar region. Three of the four patients were asymptomatic prior to the onset of jaundice. The presence of atrophy precipitated laparotomy to exclude cancer in two cases. Marked disparity in size between liver lobes precluded a hilar approach to relieve extrahepatic obstruction in two patients. Prolonged follow-up excluded coincident malignant disease. Selective liver atrophy should be considered part of the disease spectrum in primary sclerosing cholangitis.

publication date

  • January 1989



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1016/0002-9610(89)90314-0

PubMed ID

  • 2662789

Additional Document Info

start page

  • 43

end page

  • 7


  • 158


  • 1