Elevated cerebellar glucose metabolism in microvascular white matter disease: Normal aging and Alzheimer's disease Academic Article uri icon

Overview

MeSH Major

  • Aging
  • Alzheimer Disease
  • Cerebellum
  • Glucose

abstract

  • Young normal, elderly, and clinically diagnosed Alzheimer disease subjects who had undergone positron emission tomography (PET) and computed tomography (CT) examinations were studied to determine the effect of periventricular white matter lesions on cerebellar glucose metabolic rates. PET-determined cerebellar metabolic rates were elevated in subjects with periventricular white matter lesions. These results suggest the cautious use of cortical-to-cerebellar ratios in future PET or single-photon-emission CT (SPECT) studies.

publication date

  • January 1988

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1038/jcbfm.1988.80

PubMed ID

  • 3259243

Additional Document Info

start page

  • 433

end page

  • 5

volume

  • 8

number

  • 3