Cobalt plaque versus enucleation for uveal melanoma: Comparison of survival rates Academic Article Article uri icon


MeSH Major

  • Eyelids
  • Lymph Nodes
  • Radiopharmaceuticals
  • Technetium Tc 99m Sulfur Colloid


  • Two hundred and twenty-three patients treated by cobalt plaque for uveal melanoma were compared with 416 patients treated by enucleation for uveal melanoma in terms of patient survival. The median follow-up time for the patients treated by cobalt plaque was 4.3 years. Kaplan-Meier survival curves were calculated up to five years following treatment based on time to tumour-related deaths. Cox's proportional hazards multivariate analysis was performed to determine which variables were related to melanoma-related deaths while controlling for age, size, and location of the tumours. Statistically significant predictive factors were location of tumour and largest tumour dimension. There was not a statistically significant difference in survival between patients treated by cobalt plaque and those treated by enucleation.

publication date

  • January 1988



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1136/bjo.72.7.494

PubMed ID

  • 3415941

Additional Document Info

start page

  • 494

end page

  • 7


  • 72


  • 7