Definition of genetic factors in hypertension: A search for major genes, polygenes, and homogeneous subtypes Review uri icon

Overview

MeSH Major

  • Hypertension

abstract

  • Essential hypertension is a heterogeneous group of disorders with different causes. This report reviews approaches taken and results found in current studies of the genetic and environmental determinants of essential hypertension. Recent observations from the University of Utah Cardiovascular Genetics Research Clinic and published data from other studies are cited. Several biochemical tests show strong associations with hypertension and substantial major gene and/or polygenic determination including: urinary kallikrein excretion, intracellular sodium concentration, sodium-lithium countertransport, plasma haptoglobin phenotypes, MN blood groups, and familial dyslipidemia.

publication date

  • January 1988

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 2467108

Additional Document Info

start page

  • S7

end page

  • 20

volume

  • 12

number

  • SUPPL. 3