Neuropathy and IgM paraproteinemia: Differential binding of IgM M-proteins to peripheral nerve glycolipids Academic Article uri icon

Overview

MeSH Major

  • Glycolipids
  • Immunoglobulin M
  • Paraproteinemias
  • Peripheral Nervous System Diseases

abstract

  • Two patients with neuropathy and IgM paraproteinemia displayed different immunoreactivity to acidic peripheral nerve glycolipids. In one patient, immunostaining on thin-layer chromatographic plate revealed binding of the IgM to sulfated glucuronosyl paragloboside (SGPG) and sulfated glucuronosyl lactosaminyl paragloboside (SGLPG). The other IgM bound SGPG, SGLPG, and a new third glycolipid. Immunoreactivity of the IgM varies in this syndrome.

publication date

  • December 1987

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 2823182

Additional Document Info

start page

  • 1795

end page

  • 7

volume

  • 37

number

  • 11