Behcet disease Review uri icon

Overview

MeSH Major

  • Behcet Syndrome
  • Skin Diseases

abstract

  • Behçet's disease is a complex, multisystem disease that was first described in 1937 by the Turkish dermatologist, Hulusi Behçet, but may have been recognized since ancient times. In his original description, Behçet referred to a symptom complex of recurrent oral aphthous ulcers, genital aphthae, and iritis that could lead to blindness. Additional clinical manifestations include the pathergy phenomenon (the induction of a cutaneous pustular neutrophilic vascular reaction after intradermal trauma), arthritis, thrombophlebitis, erythema nodosum-like cutaneous lesions, and neurologic signs and symptoms ranging from benign intracranial hypertension to a condition resembling multiple sclerosis. The author discusses epidemiology, diagnosis, clinical aspects, pathology, clinical course of the disease, and therapy.

publication date

  • January 1987

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 3306334

Additional Document Info

start page

  • 427

end page

  • 40

volume

  • 5

number

  • 3