Primary CNS lymphoma: managing patients with spontaneous and AIDS-related disease. Review uri icon

Overview

MeSH Major

  • Acquired Immunodeficiency Syndrome
  • Brain Neoplasms
  • Lymphoma

abstract

  • Primary central nervous system lymphoma, especially that associated with AIDS, is increasing in frequency. CT scan is virtually diagnostic when it shows multiple, hyperdense, diffusely enhancing periventricular lesions. Treatment often results in a complete remission, but the overall prognosis is poor. Surgery is important diagnostically, but resection is not helpful. Corticosteroids can produce significant shrinkage, and even disappearance, of PCNSL, but cranial radiation is still the cornerstone of therapy. The addition of chemotherapy to RT is promising in non-AIDS patients but still investigational.

publication date

  • August 1987

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 3079486

Additional Document Info

start page

  • 52

end page

  • 62

volume

  • 1

number

  • 6