Subpopulations of T cells in lung biopsies from patients with pigeon breeder's disease Academic Article Article uri icon

Overview

MeSH Major

  • AIDS-Related Opportunistic Infections
  • Antiretroviral Therapy, Highly Active
  • Systemic Inflammatory Response Syndrome

abstract

  • Monoclonal antibodies were used to determine surface phenotypes of T cells in tissue obtained by open lung biopsies from patients with chronic hypersensitivity pneumonitis (pigeon breeder's disease). The results indicate that an increased number of suppressor/cytotoxic cells is present in these patients when compared with the number of helper/inducer cells. These findings, which were present within the interstitium, are consistent with those found in bronchoalveolar lavage of patients with this disease. In addition, in two-thirds of the patients there was a greater total number of helper and suppressor cells than the total count for Pan T cells. A possible interpretation of these findings might be the presence of both markers in the same cell.

publication date

  • December 1987

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1007/BF02714434

PubMed ID

  • 3108594

Additional Document Info

start page

  • 181

end page

  • 7

volume

  • 165

number

  • 1