Incidence of cancer in 98 patients with common varied immunodeficiency Academic Article Article uri icon


MeSH Major

  • Autophagy
  • Cecum
  • Disease Models, Animal
  • Sepsis


  • Ninety-eight patients with common varied immunodeficiency have been observed for periods of 1-13 years. In 1986, 78 were alive, 19 had died, and 1 could not be located. Eleven patients in the group had developed cancer; two patients had had two cancers. Of the total number of neoplastic malignancies, seven were non-Hodgkin's lymphoma, one patient had a Waldenstrom's macroglobulinemia, and nine of the patients who developed cancer were female. Cancer developed in the fifth or sixth decade of life for 10 of the 11 patients. These data show an 8- to 13-fold increase in cancer in general for patients who have this immunodeficiency and a 438-fold increase in lymphoma for females.

publication date

  • July 1987



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1007/BF00915550

PubMed ID

  • 3611296

Additional Document Info

start page

  • 294

end page

  • 9


  • 7


  • 4