Positron emission tomography of hydrocephalus. Metabolic effects of shunt procedures. Academic Article uri icon

Overview

MeSH Major

  • Cerebrospinal Fluid Shunts
  • Hydrocephalus
  • Tomography, Emission-Computed

abstract

  • Five patients with hydrocephalus were studied with carbon-11-2-deoxyglucose or 2-deoxy-2-(18F) fluoro-D-glucose and positron emission tomography both prior to and following ventricular shunting. Four subjects had communicating hydrocephalus; the fifth had aqueductal stenosis, two patients had hydrocephalus for three months or less. The three chronic patients were felt to have hydrocephalus for three years or more. After shunting ventricular size decreased in all patients, and all patients showed clinical improvement. The glucose cerebral metabolic rates increased after shunt in the two subjects with recent onset hydrocephalus but paradoxially decreased in the three chronic patients despite clinical improvement. These findings suggest that the cerebrum was metabolically hyperactive prior to shunt due to an unknown mechanism and presumably in response to the presence of hydrocephalus. A dissociation may also exist in the post-shunt period between cerebral metabolism and cerebral blood flow.

publication date

  • January 1986

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 2980520

Additional Document Info

start page

  • 435

end page

  • 9

volume

  • 369