Single-chain precursor of renal γ-glutamyl transpeptidase Academic Article uri icon

Overview

MeSH Major

  • Phospholipid Transfer Proteins

abstract

  • The two subunits of gamma-glutamyl transpeptidase (EC 2.3.2.2) are derived from a single-chain glycosylated precursor. A small fraction of the propeptide survives proteolytic processing in the rat kidney and has been purified by an immunoaffinity technique. The propeptide contains determinants for both the subunits and its amino acid composition resembles that of the dimeric enzyme. However, the propeptide exhibits less than 2% of the transpeptidase activity shown by the dimeric enzyme.

publication date

  • January 1986

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/0014-5793(86)80046-1

Additional Document Info

start page

  • 33

end page

  • 8

volume

  • 194

number

  • 1