Chronic renal failure: A significant risk factor in the development of acquired renal cysts and renal cell carcinoma. Case reports and review of the literature Academic Article Article uri icon


MeSH Major

  • Diagnostic Imaging
  • Medical Oncology
  • Neoplasms
  • Precision Medicine


  • Three male patients with end-stage renal disease on chronic hemodialysis presented with gross hematuria and were subsequently found to have acquired renal cyst disease and progressive bilateral renal cell carcinoma. There are now more than 84 similar cases in the literature, but the precise roles that renal failure and hemodialysis play in the development of renal cysts and renal neoplasms remain unclear. The high incidence of acquired renal cyst disease (45%) and the development of renal tumors (9%, with a 5% to 7% metastatic rate) in patients with end-stage renal failure clearly underscores the need for more intense radiologic monitoring.

publication date

  • January 1986



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19860501)57:9<1871::AID-CNCR2820570929>3.0.CO;2-3

PubMed ID

  • 3513944

Additional Document Info

start page

  • 1871

end page

  • 9


  • 57


  • 9