Predictability of renal allograft failure time in long-term survivors: A hypothesis
A method has been described for predicting failure time of renal allografts. Its close correlation with the actual event that occurred in 60 recipients who had lost their graft suggests a potential value for transplant investigators. There are, however, obvious exceptions to its applicability, especially when insufficient data points are available or when intercurrent illnesses unrelated to the more gradual decline of kidney function are superimposed on the data. We believe its value lies in the form of a guide for monitoring the course of experimental regimens that may abort the progression of renal insufficiency. A significantly less negative slope in calculated regression lines would herald the success of such interventions.