Reduction in the stearic to oleic acid ratio in human malignant liver neoplasms Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Hepatocellular
  • Liver Neoplasms
  • Membrane Lipids
  • Oleic Acids
  • Stearic Acids

abstract

  • Total lipid extracts of liver tissue from 14 patients with primary and secondary liver tumours were analysed for relative values of saturation of 18 carbon chain length fatty acids (C18FA). The saturation indices (ratio C18S:C18u) of the tumour areas were significantly and consistently lower than the corresponding values in the non-tumour areas (P less than 0.001). It is proposed that the relative increase in unsaturated C18FA (oleic acid) could prove to be a chemical marker reflecting deficient cellular control of the desaturation of stearic acid.

publication date

  • December 1985

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 2998886

Additional Document Info

start page

  • 347

end page

  • 8

volume

  • 11

number

  • 4