Terminal deoxynucleotidyl transferase activity in childhood leukemia Academic Article uri icon

Overview

MeSH Major

  • Early Detection of Cancer
  • Kallikreins
  • Prostate-Specific Antigen
  • Prostatic Neoplasms

abstract

  • The activity of terminal deoxynucleotidyl transferase (Tdt) was measured in mononuclear cells of 70 children with acute leukemia, in whom raised levels of Tdt were noted at diagnosis, relapse, or during remission. Serial measurements of Tdt activity were related to the percentage of blasts in the bone marrow and the clinical course of children both during therapy and after its completion. The Tdt values did not predict relapse in children with acute lymphoblastic leukemia nor did the quantitative determination correlate with the percentage of blasts in the bone marrow.

publication date

  • January 1985

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19850501)55:9<1943::AID-CNCR2820550919>3.0.CO;2-9

Additional Document Info

start page

  • 1943

end page

  • 7

volume

  • 55

number

  • 9