Hypertension and decreased graft survival in long-term kidney transplant recipients
Lupus Erythematosus, Systemic
Hypertensive patients have a significantly lower GSR than that of normotensive patients. The lower GSR does not, however, appear to be caused by hypertension per se. Rather, both low graft survival and hypertension seem to be the consequence of a low graft function associated with underlying graft pathology. Maintaining BP within normal ranges with antihypertensive agents does not appear to improve graft function and survival to the rates in normosensitive patients. In conclusion, hypertensive kidney transplant patients have low graft function and survival. Hypertension and poor graft function seem to be associated phenomena and both may reflect an underlying pathologic process in the allograft. Control of hypertension does not appear to improve graft function and survival.