VAB-6 as initial treatment of patients with advanced seminoma Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Dysgerminoma
  • Mediastinal Neoplasms
  • Retroperitoneal Neoplasms
  • Testicular Neoplasms

abstract

  • Thirty patients with advanced seminoma were treated with VAB-6. Eighteen patients were previously untreated, eight had relapsed after radiation therapy, and four had persistent disease following chemotherapy and radiation therapy. Two patients had received prior high-dose cisplatin. Twenty-four (86%) of 28 evaluable patients achieved a complete remission. Four patients had relapsed. The median disease-free follow-up of patients achieving complete remission was 32+ months. VAB-6 is effective treatment for patients with advanced seminoma, and chemotherapy is recommended as the initial therapy in all patients with stage II seminoma with disease larger than 5 cm, extragonadal seminoma, and stage III seminoma.

publication date

  • May 8, 1985

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 2579214

Additional Document Info

start page

  • 336

end page

  • 9

volume

  • 3

number

  • 3