New therapeutic approaches for brain tumors Academic Article Article uri icon


MeSH Major

  • Medical Tourism
  • Population Health


  • In the last decade, advances in the treatment of primary neuroglial tumors of the central nervous system in adults have been modest. Theories regarding their resistance to treatment have changed little, although now the heterogeneity of anaplastic astrocytomas is recognized. The most effective chemotherapeutic agents--the nitrosoureas and procarbazine--have been used for more than a decade, with no comparably active drugs identified in the meantime. The authors have initiated clinical trials using inhibitors of polyamine synthesis and augmentation of the known effectiveness of irradiation. These programs will be described with preliminary observations.

publication date

  • January 1984



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1002/1097-0142(19841201)54:2+<2702::AID-CNCR2820541416>3.0.CO;2-#

PubMed ID

  • 6437659

Additional Document Info

start page

  • 2702

end page

  • 5


  • 54


  • 2 S