Monoclonal antibody to Thy-1 enhances regeneration of processes by rat retinal ganglion cells in culture Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal
  • Antigens, Surface
  • Isoantibodies
  • Nerve Regeneration
  • Retina
  • Retinal Ganglion Cells

abstract

  • Ganglion cells were dissociated from postnatal rat retinas, identified by specific fluorescent labels, and maintained in culture on a variety of substrates. Regeneration of processes by retinal ganglion cells was enhanced when the cells were plated on glass coated with a monoclonal antibody against the Thy-1 determinant. Plain glass and glass coated with polylysine, collagen, fibronectin, or other monoclonal antibodies supported the growth of neural processes, but were less effective than antibody to Thy-1.

publication date

  • December 1984

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 6143400

Additional Document Info

start page

  • 303

end page

  • 6

volume

  • 224

number

  • 4646