Hypertension, vascular headaches, and seizures after carotid endarterectomy. Case report and therapeutic considerations Academic Article Article uri icon


MeSH Major

  • Diabetes Mellitus, Type 2
  • Hemoglobin A, Glycosylated
  • Hypoglycemic Agents


  • The following three unusual complications of carotid endarterectomy developed in a 64-year-old woman: vascular headaches, delayed hypertension, and seizures. beta-Blockade with propranolol hydrochloride had no beneficial effect on either the hypertension or the headaches. Peripheral alpha-blockade with prazosin hydrochloride resulted in prompt improvement in the patient's condition. Altered autonomic vascular control secondary to carotid sinus trauma is proposed as a possible causative mechanism for all three complications. The therapeutic implications are discussed. Based on this experience, we would caution against the use of unopposed beta-blockade in this setting and suggest that the role of prazosin in the initial management of postendarterectomy hypertension and vascular headache be explored.

publication date

  • January 1984



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1001/archinte.144.7.1489

PubMed ID

  • 6732410

Additional Document Info

start page

  • 1489

end page

  • 91


  • 144


  • 7