Orchiectomy alone in the treatment of clinical stage I nonseminomatous germ cell tumor of the testis Academic Article uri icon

Overview

MeSH Major

  • Castration
  • Teratoma
  • Testicular Neoplasms

abstract

  • Forty-five patients with clinical stage I nonseminomatous germ cell tumor of the testis (NSGCTT) were entered in a prospective clinical trial to receive no treatment other than orchiectomy until clinical evidence of relapse. Of this group, 36 patients (80%) have been continuously free of disease for a median duration of 19.5 months after orchiectomy. Nine patients (20%) have relapsed, eight within seven months of orchiectomy. Seven of nine relapsing patients have been rendered free of disease with chemotherapy and/or surgery for a median duration of seven months (range, one to 33 months) after completion of treatment; the other two patients are presently under treatment although one has progressive disease. The relapse rate was higher in patients with embryonal carcinoma than in those with teratocarcinoma, 57% versus 17%. These preliminary results imply that the omission of routine lymphadenectomy or lymph-node irradiation in clinical stage I NSGCTT deserves further trial.

publication date

  • July 19, 1984

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 6200576

Additional Document Info

start page

  • 267

end page

  • 70

volume

  • 2

number

  • 4