Specific translocations characterize Burkitt's-like lymphoma of homosexual men with the acquired immunodeficiency syndrome Academic Article uri icon

Overview

MeSH Major

  • Acquired Immunodeficiency Syndrome
  • Burkitt Lymphoma
  • Homosexuality
  • Translocation, Genetic

abstract

  • A Burkitt's-like B-cell lymphoma (BLL) has recently been shown to be associated with the acquired immunodeficiency syndrome (AIDS), which affects homosexual men. We report cytogenetic studies of two BLL tumors in homosexual men. Both tumors had chromosome translocations characteristic of Burkitt's lymphoma (BL), one the t(8;14) and the other the t(8;22). The pathway of lymphomagenesis in this disorder is discussed in the light of recent data on chromosome change and localization of immunoglobulin genes and oncogenes.

publication date

  • July 21, 1983

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 6839024

Additional Document Info

start page

  • 1265

end page

  • 8

volume

  • 61

number

  • 6