Opiates and classical conditioning: Selective abolition of conditioned responses by activation of opiate receptors within the central nervous system Academic Article uri icon

Overview

MeSH Major

  • Cerebral Ventricles
  • Conditioning, Classical
  • Receptors, Opioid

abstract

  • It has previously been shown that opiates produce selective abolition of aversively motivated classically conditioned responses in the rabbit. The experiments reported here show that these effects are mediated by specific activation of opiate receptors within the central nervous system in that this central activation is both necessary and sufficient to produce opiate-induced abolition of conditioned responding. Further characterization suggests that selective activation through opiate-mu-receptor interactions within the periaqueductal gray/periventricular region of the fourth ventricle may be critical in mediating this abolition.

publication date

  • December 1982

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC347388

PubMed ID

  • 6296841

Additional Document Info

start page

  • 7598

end page

  • 602

volume

  • 79

number

  • 23 I